Getting a TLC patch in March 2018 to add howl that will initiate the pack bonus for 5 minutes, will be able to sniff out players or creatures with less than 50% health, and will be able to detect explorer notes.
Direwolves are very fast, they have very much health, really good malee and are kinda easy to tame. They are bolable and easy to tranq out, visit the northen Cave Of Strong for a high level, somewhere around 400-600
What I usually do is I make a boat and expand it and a large gate with fence around it, not walls. I then go to tundra, park near an iceberg,place bear traps on the ice burg, shoot wolves so they come towards the iceberg and then shoot them with tranqs.
You can't escape them, so don't try, you can't fight them, so don't try, you can't help your level 999 specially bred mutated giga, so don't try, just stand calmly and don't try to fight, just let the wolves eat you, at least then you'll have an interesting funeral being eaten by ravenous wolves.