Besides the giga this is the hardest dinosaur to tame, note you will need a lot of narcotics and food. Before you begin the tame I recommend at least 2 to 3 full scuba suits for obvious reasons. You need to have at least a Ichthyosaurs or Megalodon, so you can actually move around and find a decent one. Once you find one you want to tame simply start shooting at it with the crossbow. Now right when you get his attention swim up, you should notice the Mosasaurs stops following you after a certain height. The Mosasurs cannot go higher than wherever it stopped. So simply park your water Dino above it and keep shooting it. If it runs off keep doing the same thing over and over again. Sooner or later you will take him down. Good job! Then simply use this app to figure out how many narcotics/food you will need to tame it. Once it is done enjoy your king of the water.
The Mosasaurus is a deepsea creature, that means you can easily knock him out with this Trick. (you should use a basilosaurus because of his health and the immunity effects)
1) Swimm down to the deepsea
2) Let the Mosa follow you up
3) If you swimm high enought he will stop chasing you
4) When he Stops chasing you, just shoot at him with tranqs (the higher your Crossbow damage the faster he gets knocked)
5) Repeat the first steps if he swimms too far away from you
6) knock him out and feed him some Quetzal Kibbel
7) Enjoy your Aquatic Giant
BONUS TIPP: He spawn around the carno Island and i would recommend to not go too far from your basilosaurus while shooting the Mosa Because you are f*cked if some eals appear and you cant mount your Basilo to kill them (He is immune to the Shocking effect)
Best way to Tame a Mosa or at least what I do is. . .
I hit an ammonite and with the agro effect the Mosa should follow me to the surface, once the effect of the ammonite passes the Mosa couldn't return to the water and be stuck on the surface and u can shoot him easy from the Coast
This works with other animals like plesi, dunkleo, etc, u can even kill Alpha mosa with this trick.
JUST TAME A SQUID GRAB THE MOSA,DISMOUNT THE SQUID.....and put the Squid on passive I will no let go of the mosa.AND THEN THE SQUID WILL BE DOING TORPOR AND ALSO YOU CAN HARPOON IT OUT AND TAAAAAAAAAAMMMMMMMMMMMMMME!!!!