Titanoboas cannot be knocked out with torpor weapons; instead, trap one safely, wait for it to become passive, and feed it fertilized eggs from your inventory. Once tamed, it can be kept in a secure farm to produce eggs for valuable kibble and can defend an area or inflict strong torpor, though its egg-only diet limits its practicality. When encountering one, maintain distance with ranged weapons, keep backing away without exhausting your stamina, avoid relying on low obstacles, and use stimulants or stimberries if bitten.