Itsy bitsy spider came up the water spout...
OUT CAME THE GUN AND WIPE THE SPIDER OUT

Rexes, Rexes, more Rexes, bring rocket launchers, bring friends with rocket launchers.......and Rexes.

Bring 19 Megatherium and 1 Yutyrannus. Can and will kill Lysrix on any difficulty.
Replace 1 Mega with a Daeodon for more survivability.

Always do level 3 beacuse doing all 3 is a wast of resources and if you beat level 3 you get the rewards for level 1 and 2 also.

Bring lots of megatheriums, they have a damage boost against bugs, wait, spiders are bugs right? RIGHT?!?! Oh and two mate boosted yutyranuses. And rex's.

I went in with two Daeodons eight megatheriums a yutyrannus and one megalania to kill the alpha version. I climbed to the ceiling of the cave with the megalania and blasted it with rockets from the roof while the megatherium tanked it and the yuty gave the Megas a buff and the daeodon healed

Use mutated megatherium

All you need is a dodo and a slingshot I mean really cmon guys

Megatheriums are great due to the buff. They also kill the minions instantly

Bring 10 Rex’s 2 yutys 3 pigs all your friends and 5 bug killers

Always do the level 3 boss because doing them all takes more resources and if you complete level 3 you get the rewards from 1 and 2 also.

I was on single player, did all the official work necessary to face the alpha version. Just to make it interesting I spawned a lvl 1500 rex.... she still took it down. R.I.P. Rexy.

On valguero, there is a cave in which the broodmother can spawn on its own.

Ah, the Broodmother. Commonly mistaken for a jellyfish.

On valguero you might find one in the spider ravine in the redwoods. It despawned after a while but I think it was only there to boost spider spawn rates or something

Trap it with a lot of rexes and eat it

When you take on the brood. Rush it. If you get your rexs to surround it you can pin it so it doesnt do its poison attack. Rexs will need 30k hp 800 melle and you will need 10. For Alpha i suggest 85+ saddles 40k hp rexs.

Bring an army of megatheriums they'll destroy her into pieces

When in the Broodmother Lysrix arena, bring 10 mutated megatheriums, these guys have a huge buff against bugs. Don’t forget, if things go wrong, bola your friends.

19 Therizinosaur's and 1 high lvl yuty should do the trick