Rockwell cannot be tamed through normal gameplay, so confronting him requires entering his arena with a prepared team, equipment, and supplies. As the Aberration boss, his main utility is providing an Ascension reward when defeated, while his former scientific contributions offer little practical benefit in his current form. Use a stamina-trained Rock Drake for mobility, a powerful shotgun to destroy his tentacles, backup Hazard protection, and strong creatures such as Megalosaurs or Reapers for damage. Avoid his energy attacks, use a light pet to manage Nameless and Reapers, and attack his exposed heart whenever it becomes vulnerable.