These suckers hunt in packs so be careful, and as with most dangerous animals, you don't have to be faster than the dire wolf......just faster than the person running next to you

On SE they can be found alone in the desert, needles to say they are still dangerous as their speed and attack can kill low level survivors in seconds.
Advise is take bolas and then poke with spears

Be wary if you think you’ve won.
In numbers, we tend to come.
We typically thrive
in 3 to 5,
So be suspicious when you see only one.

These guys are strong as anything so if you see one on scorched earth don't put down a tent they can destroy (I found out)