Dododex users say:
The Megatherium is best tamed inside a sturdy stone or metal trap by knocking it unconscious and feeding it Giant Bee Honey, raw mutton, or suitable kibble while protecting it from predators. It is a durable, high-weight mount that efficiently gathers berries, fiber, thatch, chitin, keratin, and other resources, while also excelling in combat and caves. Killing insects grants it a powerful enraged combat boost, making it highly effective against swarms and insect-heavy encounters. When encountering one, avoid fighting it while its orange or red aura is active, and use a secure trap, a durable tank, and ranged attacks while keeping insects and chitin-bearing creatures away.