ALWAYS break the hive with ranged attacks. If you choose to melee it,drones will continuously spawn from it infinitely, and they will repair the hive, so best to shoot it down and kill all the drones before attempting a tame. Oh, and the queen will spawn more drones periodically, so bee careful.
If you want to tame one, the easiest way is to get a dire bear and break the nest, because they are immune to bees. Use it to break the nest, then when the nest beaks, make sure you have full ghille armor and bug repellent, and tame it with simple kibble. You can then go to the bee and press the 'aquire nest' button, and it will give you a bees nest. You can place this on any natural ground, but no human made floors. Put rare flowers into it, and it will produce giant bee honey over time. Rare flowers can be harvested from plants in the swamps across the island, but beware of the creatures that dwell there. When you go into your bees nest to gather honey, you will get the bee effect and start taking damadge, even though it is your own bees nest.
The best way I’ve found to tame the. Was with a flying shoulder pet - Sinomacrops or Dimorph are best just don’t forget to turn off auto scream on sino.
Whistle your pet to attack the hive and run a ways away so you’re just out of render range. You’ll have to figure out the right range, but if you get far enough away the bees won’t spawn, and when the hive breaks the queen won’t run or spawn bees.
Desmodus actually is good for taming these just hit their nest and fly side to side and kill the workers then keep watch of the health once it’s low shoot it with a arrow and she should come out then just feed her 3 rare flowers.