I was taking a level 44 dire bear, he was at 94% tamed and then a Thyloceo came out of nowhere and killed him, raptors and Carnos also don’t like dire bears, I would recommend bringing a Parasaurolophus once you knock out the bear do you can detect incoming enemies who may want to attack it
To make honey last practically forever, make a fishing rod and equip honey, that is about to spoil, to the fishing rod, then un-equip it. It should refresh the spoil timer. Does not work with leech blood. Tested on PS4.
Direbear have little health compared to torpor. Keep a few tamed dodos at your ramp trap. When you've shot the bear enough for it to be bloody, throw in a dodo. It will instantly kill and eat it and start regenerating health. Give it a moment or two and continue darting. Happy hunting!