Don’t even bother with trying to fight a wild one. And if you DO manage to bring enough firepower to even stand a chance, the last thing you will see are two glowing eyes as you realize your ascendant shotgun did nothing but piss it off. Just run when you see one.
If one is encountered near water, you can simply lure it out to sea with a flyer and it will swiftly drown. Given the water is deep enough. If encountered inland not near water. Pray to the overseers you have something fast enough to out run it. Then promptly die because they're as fast as a mad Hispanic mother with a shoe. Not as deadly as one though.