Get two max level dire wolfs level them. Breed them and get a pup keep it even if the stats are trash. Get good imprint and level it outside the cave a bit. Use a gas mask from the snow cave, I already gave my strategy, I recommend that you just bring this and food. You don’t need ascendant flak believe me just use strategy, keep biting careful bo to dismount. I have farmed this artifact and using a dire wolf ascendant chitin helmet on, and gas mask Mastercraft, you don’t need to be so many items. The loot is riot gear bps, erie pistol, rockwell nirvana tonic note, potent dust, sword bps, assault rifle, and revival platform. It is easy I have done this seven literal times. Keep surviving survivor. Boss Slayer.

No you can't tame the spiders in this cave unless if you kill it and resummon it by revive platform