The Lesser Antidote cures Swamp Fever and Mega Rabies, and players report that it can also prevent certain negative effects such as bleeding, hangovers, or Noglin-related problems. It can be crafted in a mortar and pestle, preserved in a preserving bin, and some maps or creatures provide alternate ingredients or substitutes. On supported versions, feeding it to a tame may grant temporary immunity, making it useful before fighting creatures that inflict debilitating effects.